Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is characterized by an increased risk of colorectal cancer as well as cancers of the endometrium, ovary, stomach, small intestine (usually the duodenum and jejunum), hepatobiliarytract, upper urinary tract (transitional carcinoma of the ureter and renal pelvis), glioblastoma, and skin.

HNPCC is subdivided into Lynch Syndrome I (familial colon cancer) and Lynch Syndrome II (HNPCC associated with other cancer of the gastrointestinal system or the reproductive system).

Opaldia offers specific mutation screens as well as whole gene & rearrangement analyses.